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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8313 | HCH6-1 | Others | |
HCH6-1 is a competitive Formyl peptide receptor 1 (FPR1) antagonist. | |||
T9089 | FTO-IN-1 | UUN44923 | Others |
UUN44923 is a FTO inhibitor. It may be useful for treating diseases assocd. with FTO targets, obesity, metabolic syndrome (MS) , type 2 diabetes (T2D) , Alzheimer's diseases, breast cancers, small- cell lung cancers, a h... | |||
T6978 | Almitrine mesylate | Almitrine dimesylate,Almitrine bismethanesulfonate,Almitrine bismesylate | Potassium Channel |
Almitrine mesylate (Almitrine dimesylate) inhibits selectively the Ca2+-dependent K+ channel and that in rat chemoreceptor cells,used in the treatment of hypoxemic chronic lung diseases. | |||
T39719 | Nrf2 activator-1 | Nrf2 activator-1 | Nrf2 |
Nrf2 activator-1 is a potent activator of NF-E2-related factor 2 (Nrf2).Nrf2 activator-1 can be used to study COPD and other respiratory diseases including asthma, acute lung injury (ALI), acute respiratory distress synd... | |||
T25131 | AZD8309 | AZD 8309,AZD-8309 | Glutathione Peroxidase , CXCR |
AZD8309 is a potent, orally available antagonist of the chemokine receptor CXCR2 that regulates neutrophil transport, significantly reduces MPO in the pancreas and lung, and decreases trypsin and elastase activity in the... | |||
T60522 | Letosteine | Viscotiol | Others |
Letosteine (Viscotiol) is an orally active, effective, and safe expectorant that can be used in the study of acute or chronic respiratory diseases, for example, bronchopulmonary disease. Letosteine dissolves bronchial mu... | |||
T36454 | 1-Stearoyl-rac-glycerol | ||
1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid at the sn-1 position. 1-Stearoyl-rac-glycerol levels are decreased in tumor tissue in a mouse model of azoxymethane-induced colorectal carcinogenes... | |||
T5S2347 | Deoxyshikonin | Arnebin 7 | Others , HIF/HIF Prolyl-Hydroxylase , Antibacterial |
1. Deoxyshikonin (Arnebin 7) may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphatic microvascular endothelial cells (HMVEC-dLy) ... | |||
T29969 | AMG-126737 | 105RSZ5CNS,AMG 126737,SCHEMBL7986111 | |
AMG-126737 is an effective human lung mast cell trypsin inhibitor with potential therapeutic effect in lung diseases. | |||
T15354 | FTY720 (S)-Phosphate | (S)-FTY720 phosphate,(S)-FTY720P | Others |
FTY720 (S)-Phosphate is an S1P receptor 1 (S1PR1) agonist. It is used in the research of acute inflammatory diseases such as acute lung injury. | |||
T70616 | ACT-672125 | ||
ACT-672125 is a Potent CXCR3 Antagonist with Therapeutic Potential in Autoimmune Diseases. ACT-672125 showed good physicochemical properties and safety profile. In a proof-of-mechanism model of lung inflammation, ACT-672... | |||
T21074 | Dexamethasone acetate | Dexamethasone 21-acetate monohydrate,Decadron-LA,Decadron | |
Dexamethasone acetate is an adrenocortical steroid. It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, asthma, severe allergies, chronic obstructive lung disease, bra... | |||
T78091 | (S)-FTY720-phosphonate | LPL Receptor | |
FTY720 (S)-Phosphate, an S1P receptor 1 (S1PR1) agonist, is utilized in studying acute inflammatory diseases, including acute lung injury. | |||
T76526 | Ac-D-DGla-LI-Cha-C | ||
Ac-D-DGla-LI-Cha-C is a potent peptide inhibitor of the HCV protease, applicable in research targeting a range of diseases, including cancer, autoimmune, fibrotic, inflammatory, neurodegenerative, infectious, lung, heart... | |||
T71089 | PF-00956980 | ||
PF-00956980 is a reversible pan-JAK inhibitor, exhibiting IC50 values of 2.2 μM for JAK1, 23.1 μM for JAK2, and 59.9 μM for JAK3. It is utilized in the study of lung and skin inflammatory diseases. | |||
T63761 | ACT-660602 | ||
ACT-660602 is an orally active chemokine receptor CXCR3 antagonist (IC50: 204 nM). ACT-660602 inhibits T cell migration and has shown significant effects in an in vivo model of acute lung injury. ACT-660602 can be used t... | |||
T63809 | Ansornitinib | ||
Ansornitinib is an oral, active dual kinase inhibitor that inhibits platelet-derived growth factor receptor (PDGFR) and vascular endothelial growth factor receptor (VEGFR2).Ansornitinib is an antifibrotic agent that can ... | |||
T63169 | MIF2-IN-1 | ||
MIF2-IN-1 (compound 5d) is a potent MIF2 tautomerase inhibitor (IC50: 1.0 μM). MIF2-IN-1 inhibits the proliferation of non-small cell lung cancer cells by arresting the cell cycle through the MAPK pathway. MIF2-IN-1 has ... | |||
T63325 | ATX inhibitor 9 | ||
ATX inhibitor 9 is a thickened heteroaryl derivative compound and a potent inhibitor of ATX. Among them Autotaxin (ATX), also known as ENPP2, is a secreted enzyme highly expressed mainly in lung cancer cells, bronchial e... | |||
T63630 | Gefitinib dihydrochloride | ||
Gefitinib dihydrochloride is a potent, selective, orally active EGFR tyrosine kinase inhibitor (IC50: 33 nM). Gefitinib dihydrochloride selectively inhibits EGF-stimulated tumor cell growth with an IC50 value of 54 nM an... |