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Search Results for " lung diseases "

20

Compounds

Cat No. Product Name Synonyms Targets
T8313 HCH6-1 Others
HCH6-1 is a competitive Formyl peptide receptor 1 (FPR1) antagonist.
T9089 FTO-IN-1 UUN44923 Others
UUN44923 is a FTO inhibitor. It may be useful for treating diseases assocd. with FTO targets, obesity, metabolic syndrome (MS) , type 2 diabetes (T2D) , Alzheimer's diseases, breast cancers, small- cell lung cancers, a h...
T6978 Almitrine mesylate Almitrine dimesylate,Almitrine bismethanesulfonate,Almitrine bismesylate Potassium Channel
Almitrine mesylate (Almitrine dimesylate) inhibits selectively the Ca2+-dependent K+ channel and that in rat chemoreceptor cells,used in the treatment of hypoxemic chronic lung diseases.
T39719 Nrf2 activator-1 Nrf2 activator-1 Nrf2
Nrf2 activator-1 is a potent activator of NF-E2-related factor 2 (Nrf2).Nrf2 activator-1 can be used to study COPD and other respiratory diseases including asthma, acute lung injury (ALI), acute respiratory distress synd...
T25131 AZD8309 AZD 8309,AZD-8309 Glutathione Peroxidase , CXCR
AZD8309 is a potent, orally available antagonist of the chemokine receptor CXCR2 that regulates neutrophil transport, significantly reduces MPO in the pancreas and lung, and decreases trypsin and elastase activity in the...
T60522 Letosteine Viscotiol Others
Letosteine (Viscotiol) is an orally active, effective, and safe expectorant that can be used in the study of acute or chronic respiratory diseases, for example, bronchopulmonary disease. Letosteine dissolves bronchial mu...
T36454 1-Stearoyl-rac-glycerol
1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid at the sn-1 position. 1-Stearoyl-rac-glycerol levels are decreased in tumor tissue in a mouse model of azoxymethane-induced colorectal carcinogenes...
T5S2347 Deoxyshikonin Arnebin 7 Others , HIF/HIF Prolyl-Hydroxylase , Antibacterial
1. Deoxyshikonin (Arnebin 7) may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphatic microvascular endothelial cells (HMVEC-dLy) ...
T29969 AMG-126737 105RSZ5CNS,AMG 126737,SCHEMBL7986111
AMG-126737 is an effective human lung mast cell trypsin inhibitor with potential therapeutic effect in lung diseases.
T15354 FTY720 (S)-Phosphate (S)-FTY720 phosphate,(S)-FTY720P Others
FTY720 (S)-Phosphate is an S1P receptor 1 (S1PR1) agonist. It is used in the research of acute inflammatory diseases such as acute lung injury.
T70616 ACT-672125
ACT-672125 is a Potent CXCR3 Antagonist with Therapeutic Potential in Autoimmune Diseases. ACT-672125 showed good physicochemical properties and safety profile. In a proof-of-mechanism model of lung inflammation, ACT-672...
T21074 Dexamethasone acetate Dexamethasone 21-acetate monohydrate,Decadron-LA,Decadron
Dexamethasone acetate is an adrenocortical steroid. It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, asthma, severe allergies, chronic obstructive lung disease, bra...
T78091 (S)-FTY720-phosphonate LPL Receptor
FTY720 (S)-Phosphate, an S1P receptor 1 (S1PR1) agonist, is utilized in studying acute inflammatory diseases, including acute lung injury.
T76526 Ac-D-DGla-LI-Cha-C
Ac-D-DGla-LI-Cha-C is a potent peptide inhibitor of the HCV protease, applicable in research targeting a range of diseases, including cancer, autoimmune, fibrotic, inflammatory, neurodegenerative, infectious, lung, heart...
T71089 PF-00956980
PF-00956980 is a reversible pan-JAK inhibitor, exhibiting IC50 values of 2.2 μM for JAK1, 23.1 μM for JAK2, and 59.9 μM for JAK3. It is utilized in the study of lung and skin inflammatory diseases.
T63761 ACT-660602
ACT-660602 is an orally active chemokine receptor CXCR3 antagonist (IC50: 204 nM). ACT-660602 inhibits T cell migration and has shown significant effects in an in vivo model of acute lung injury. ACT-660602 can be used t...
T63809 Ansornitinib
Ansornitinib is an oral, active dual kinase inhibitor that inhibits platelet-derived growth factor receptor (PDGFR) and vascular endothelial growth factor receptor (VEGFR2).Ansornitinib is an antifibrotic agent that can ...
T63169 MIF2-IN-1
MIF2-IN-1 (compound 5d) is a potent MIF2 tautomerase inhibitor (IC50: 1.0 μM). MIF2-IN-1 inhibits the proliferation of non-small cell lung cancer cells by arresting the cell cycle through the MAPK pathway. MIF2-IN-1 has ...
T63325 ATX inhibitor 9
ATX inhibitor 9 is a thickened heteroaryl derivative compound and a potent inhibitor of ATX. Among them Autotaxin (ATX), also known as ENPP2, is a secreted enzyme highly expressed mainly in lung cancer cells, bronchial e...
T63630 Gefitinib dihydrochloride
Gefitinib dihydrochloride is a potent, selective, orally active EGFR tyrosine kinase inhibitor (IC50: 33 nM). Gefitinib dihydrochloride selectively inhibits EGF-stimulated tumor cell growth with an IC50 value of 54 nM an...
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